ADRA2C Antilichaam - C-terminaal gebied: Biotine (ARP59968 P050-Biotine)

Adrenoceptor alpha 2C

ADRA2L2, ADRARL2, ADRA2RL2, ALPHA2CAR

152

P18825

NP_000674.2

Human, Pig

The immunogen is a synthetic peptide directed towards the C-terminal region of human ADRA2C

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Human: 100%; Pig: 85%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

41kDa

Wet Ice

374

ADRA2C

ADRA2C

Rabbit

Alpha-2C adrenergic receptor

NM_000683.3

RAGAEGGAGGADGQGAGPGAAESGALTASREWGGERGRPLCLPPSARGCF