ADRBK1 Antilichaam, KO gevalideerd

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

156

P25098

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 440-689 of human ADRBK1 (NP_001610.2) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Immunology, Neuroscience, Signal Transduction

Affinity purification

HT-29

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 80kDa

IgG

ADRBK1

Mouse spleen

Mouse brain

Adrenergic, beta, receptor kinase 1

Homo sapiens

ADRBK1, adrenergic, beta, receptor kinase 1, BARK1, BETA-ARK1, GRK2, beta adrenergic receptor kinase 1, BARK

WB, IHC

Liquid