ADROPIN Antilichaam

ADROPIN is a recently identified protein that has been implicated in the maintenance of energy homeostasis and insulin resistance (1-3) . ADROPIN expression is regulated by energy status and dietary nutrient content and is altered by obesity and regulates the expression of hepatic lipogenic genes and adipose tissue peroxisome proliferator-activated receptor gamma (PPAR-gamma) (1) . ADROPIN levels increase with dietary fat content (2) . ADROPIN has also been proposed to play a role in the regulation of endothelial function (3) .

375704

Q6UWT2

NP_940975

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Obesity

ADROPIN antibody is affinity chromatography purified via peptide column.

Cat. No. 1303 - Human Brain Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (94%)

ADROPIN antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

ADROPIN antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

ADROPIN antibody is human, mouse and rat reactive. Despite its predicted molecular weight, ADROPIN often migrates at a higher than expected molecular weight in SDS-PAGE.

ENHO

Cat. No. 10-301 - Human Brain Tissue Slide

Energy homeostasis associated

Homo sapiens

Kumar KG, Trevaskis JL, Lam DD, et al. Identification of Adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism. Cell Metab. 2008; 8:468-81.

Kumar KG, Zhang J, Gao S, et al. Adropin deficiency is associated with increased adiposity and insulin resistance. Obesity 2012; 1394-402.

Lovren F, Pan Y, Quan A, et al. Adropin is a novel regulator of endothelial function. Circulation 2010; 122:S185-92.

ADROPIN Antibody: UNQ470, C9orf165, UNQ470/PRO830, Adropin, Energy homeostasis-associated protein

ELISA, WB, IHC-P, IF

58218977

Liquid