Aducanumab (Mouse IGG2a)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Aducanumab (Mouse IGG2a) is a monoclonal antibody that selectively targets aggregated amyloid-beta (Aβ). The variable region of Aducanumab (Mouse IGG2a) is consistent with that of Aducanumab , while the constant region is of Mouse IGG2a sequence. Aducanumab (Mouse IGG2a) has strong selectivity for Aβ fibrils with EC50s of >1 μM and 0.2 nM for monomeric Aβ1-40 and fibrillar Aβ1-42, respectively. Aducanumab (Mouse IGG2a) can be used for Alzheimer's disease (AD) research[1].
12352203
Amyloid-β
Neuronal Signaling
Neuroscience-Neurodegeneration
Neurological Disease
99.0
[Aducanumab(MouseIGG2a)]
(147.019 kDa)
[1]Arndt JW, et al. Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-β. Sci Rep. 2018 Apr 23;8 (1) :6412.
Dry Ice
-80°C
http://file.medchemexpress.com/batch_PDF/HY-P990109/Aducanumab-Mouse-IGG2a-SDS-MedChemExpress.pdf
Inhibitory Antibodies
No Development Reported
Beschrijving
Aducanumab (Mouse IGG2a) is a monoclonal antibody that selectively targets aggregated amyloid-beta (Aβ). The variable region of Aducanumab (Mouse IGG2a) is cons
Specificaties
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