AE 51310
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
AE 51310 is a potent antagonist of the GPCR OPN4/melanopsin (Ki = 0.096 nM human OPN4) .1 OPN4 regulates circadian rhythms, pupil functions, melatonin expression, cognition, and sleep. OPN4 has been found to bind G11 in lung cancer cells modulating PKC activation leading to activation of BRAF/MEK/ERK signaling pathways. AE 51310 decreased the growth and proliferation of both LG17 and LG55 lung cancer tumors in mouse xenograft models.
Unconjugated
White solid
-20°C
Beschrijving
AE 51310 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
1,4- Dioxane Pure
1041330 500
500 mL
Benzonase ELISA Kit
EG23601S
96 Tests
Not I Restriction Enzyme
B2016623
500 Units
K562-HLA-G0101 Overexpressing Cell Line
RG-1214
5x 10^6
Yeast Poly (A) Polymerase
RNT-006-S
30000 Units
Arachis hypogaea Lectin (PNA) - Biotinylated
21510020-1
5mg
Arachis hypogaea lectin (PNA)
05-0116-10mg
10 mg
Anti-APOE2 mouse monoclonal antibody
TD-AB0132
100 µg