AES Antilichaam - middengebied: Biotine (ARP32323 P050-Biotine)

Amino-terminal enhancer of split

AES, GRG, ESP1, GRG5, AES-1, AES-2, Grg-5

166

Q14CJ1

NP_945320

Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human AES

AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes.The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.

MFAP1; MBNL1; SMAD3; LMO2; LMO1; KRT31; DDX6; CRX; BYSL; BCL6; AES; AEN; CARD9; PARVG; LSM2; HOMEZ; MAGOHB; RNF31; VPS37C; C1orf109; OSGIN1; MED4; PRPF31; GORASP2; KANK2; LDOC1; MTUS2; DIP2A; NCDN; BAHD1; IKZF3; U2AF2; RBPMS; FRS3; NEK6; CALCOCO2; ABI2; T

Biotin

Polyclonal Antibody

WB

Affinity Purified

AES is supported by BioGPS gene expression data to be expressed in DU145

0.5 mg/ml

Cow: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

29kDa

Lim, J., (2006) Cell 125 (4), 801-814

Wet Ice

264

AES

AES

Rabbit

Amino-terminal enhancer of split

NM_198969

HKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNSIIRQ