
AF12198
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
185413-30-3
C04444-1mg
AF12198 is a potent, selective and specific peptide antagonist for human type I interleukin-1 receptor (IL1-R1) (IC50=8 nM) but not the human type II receptor (IC50=6.7 μM) or the murine type I receptor (IC50>200 μM) . AF12198 inhibits IL-1-induced IL-8 production (IC50=25 nM) and IL-1-induced intercellular adhesion molecule-1 (ICAM-1) expression (IC50=9 nM) in vitro. AF12198 has anti-inflammatory activities and blocks responses to IL-1 in vivo.
3 years-20°C powder 2 years-80°C in solvent
Beschrijving
AF12198 Beschikbaar in 1 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
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