AF/LE Gezuiverd antimens IL-10 Antilichaam[JES3-9D7]

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, prolifeRation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

IL-10

3586

P22301

Human

Recombinant Human IL-10 protein

Interleukin; RP11-262N; CSIF; GVHDS; IL-10; IL10A; TGIF; IL10; Cytokine synthesis inhibitory factor; Interleukin-10; MGC126450; MGC126451; RP11-262N9.1

JES3-9D7

None (AF/LE)

FCM

Immunology; Cancer

>98%, Protein A/G purified

≥ 1 mg/mL

66

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Ice bag

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

https://789.bio/eb/ENu583Uh

Rat IgG1, κ