AF/LE Gezuiverde anti-muis CD45RO/B220 Antilichaam[RA3-6B2]

CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

CD45RO

Mouse

Recombinant Mouse B220 protein

RA3-6B2

None (AF/LE)

FCM

>98%, Protein A/G purified

≥ 1 mg/mL

66

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Ice bag

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

https://789.bio/eb/ahJNkWwF

Rat IgG2a, κ