AFP Antilichaam

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

174

P02771

Human, Mouse, Rat

Recombinant protein of human AFP.

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Stem Cell

Affinity purification

HepG2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 75kDa

IgG

AFP

Mouse liver

Mouse kidney

Rat plasma

Rat liver

Alpha-fetoprotein

Homo sapiens

AFP Antibody: FETA, HPAFP, Alpha-fetoprotein, Alpha-1-fetoprotein

WB, IF, IP

Liquid