Ageladine
Gecertificeerd

Ageladine

Catalog #: TN8932-01
Maat: 10 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

CAS Number

2757574-06-2

Target

MMP

Related Pathways

Proteases/Proteasome

Bioactivity

Ageladine A dihydrochloride, derived from the marine sponge Agelas nakamurai, serves as a matrix metalloproteinase (MMP) inhibitor with anti-angiogenic properties. It inhibits MMP-2, MMP-1, MMP-8, MMP-9, MMP-12, and MMP-13, with IC50 values of 4.65 μM, 2.79 μM, 907.12 nM, 1.83 μM, 767.57 nM, and 1.09 μM, respectively. As a pH-sensitive membrane-permeable dye, it emits fluorescence in the blue-green range when excited by ultraviolet light, with a maximum absorption peak at 370 nm. Additionally, Ageladine A dihydrochloride is used as a reliable and stable fluorescent pH sensor to detect intracellular pH changes.

Smiles

BrC1=C(Br)NC(C2=NC=CC3=C2N=C(N)N3)=C1.Cl.Cl

Molecular Formula

C10H9Br2Cl2N5

Molecular Weight

429.926

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Beschrijving

Ageladine Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamAgeladine
Categorie
Beschikbare grootte10 mg
CatalogusnummerTN8932-01