Agerafenib (CEP-32496)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1188910-76-0
RXDX-105
C18091-10mg
CSF-1R
Protein Tyrosine Kinase
CC (C) (C1=CC (=NO1) NC (=O) NC2=CC (=CC=C2) OC3=NC=NC4=CC (=C (C=C43) OC) OC) C (F) (F) F
C24H22F3N5O5
Agerafenib (CEP-32496) is a highly potent inhibitor of BRAF (V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret (c-Ret), PDGFRβ and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2. Phase 1/2.
2 years -80 in solvent
Beschrijving
Agerafenib (CEP-32496) Beschikbaar in 10 mM / 1 mL. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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