Agomelatinehydrochloride
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1176316-99-6
S-20098 hydrochloride
C03665-5mg
MT Receptor
Neuronal Signaling
Agomelatine hydrochloride (S-20098 hydrochloride) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively. It is also a selective antagonist of 5-HT2C receptors with pKis of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively. Blockade of these receptors enhances adrenergic and dopaminergic transmission in the frontocortical regions.
Beschrijving
Agomelatinehydrochloride Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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