AGPAT2 Antilichaam - C-terminal regio : HRP (ARP44637_T100-HRP)

1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)

BSCL, BSCL1, LPAAB, 1-AGPAT2, LPAAT-beta

10555

Q5VUD3

NP_001012745

Human, Pig

The immunogen is a synthetic peptide directed towards the C terminal region of human AGPAT2

AGPAT2 is a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in its gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance.This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

ABCG8; PHRF1; PHF11; ANKRD28; SLC23A2; GMPS; UBC

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

0.5 mg/ml

Human: 100%; Pig: 91%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

27kDa

Niesporek, S., (2005) Br. J. Cancer 92 (9), 1729-1736

Wet Ice

246

AGPAT2

AGPAT2

Rabbit

1-acyl-sn-glycerol-3-phosphate acyltransferase beta

NM_001012727

LEAIPTSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPA