(±) -Aiphanol
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
578020-29-8
COX, VEGFR
Angiogenesis, Immunology/Inflammation, Neuroscience, Tyrosine Kinase/Adaptors
(±) -Aiphanol, a newly identified stilbenolignan analog, demonstrates notable anti-inflammatory properties by inhibiting COX-1 and COX-2. It shows a robust inhibitory effect on COX-1 (IC 50 = 1.9 μM) and a milder effect on COX-2 (IC 50 = 9.9 μM) [1]. Additionally, (±) -Aiphanol effectively inhibits VEGFR2 with an IC 50 of 0.92 μM, blocking angiogenesis and inducing apoptosis through VEGFR2 and COX2 inhibition. It is also orally active [2].
C(O)[C@@H]1[C@H](OC=2C(O1)=CC=C(/C=C/C3=CC(O)=CC(O)=C3)C2)C4=CC(OC)=C(O)C(OC)=C4
C25H24O8
452.45
Ice Packs
-20°C
Beschrijving
(±) -Aiphanol Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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