AIRE Antilichaam

9007-83-4

[AIRE]

326

Human

Store at -20 degree C. Stable for 12 months from date of receipt.

AIRE Antibody detects endogenous levels of total AIRE.<br>Tissue Specificity: Widely expressed. Expressed at higher level in thymus (medullary epithelial cells and monocyte-dendritic cells), pancreas, adrenal cortex and testis. Expressed at lower level in the spleen, fetal liver and lympHnodes. In secondary lymphoid organs, expressed in a discrete population of bone marrow-derived toleregenic antigen presenting cells (APCs) called extrathymic AIRE expressing cells (eTAC) (at protein level). Isoform 2 and isoform 3 seem to be less frequently expressed than isoform 1, if at all.

[AIRE; AIRE; APS1; APSI; PGA1; AIRE1; APECED; APECED; APECED protein]

[AIRE]

[autoimmune regulator; Autoimmune regulator; autoimmune regulator; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; autoimmune regulator; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein]

4557291

NP_000374.1

NM_000383.3

O43918