AIRE Antilichaam - middengebied: Biotine (ARP37991 P050-Biotine)

Autoimmune regulator

APS1, APSI, PGA1, AIRE1, APECED

326

O43918

NP_000374

Human

The immunogen is a synthetic peptide directed towards the middle region of human AIRE

AIRE is a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript p

TUBB; RAVER1; TUBA1C; TMPRSS13; CCDC87; FAT1; GIGYF2; SRRM2; TUBB4B; EIF4EBP3; UBB; HSP90AB1; HSPA8; HSPA5; HSPA1L; HSPA1A; ATP4A; HIST3H3; HDAC2; HDAC1; DAXX; AIRE; UBAC1; HIST1H3A; HIST2H2BE; HSPA4; SRSF1; SMC1A; XPO1; TOP2A; SSRP1; SNRPD3; SNRPB; SRSF3

Biotin

Polyclonal Antibody

WB

Affinity Purified

AIRE is supported by BioGPS gene expression data to be expressed in OVCAR3

0.5 mg/ml

Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

58kDa

Ilmarinen, T., (2008) Mol. Immunol. 45 (7), 1847-1862

Wet Ice

545

AIRE

AIRE

Rabbit

Autoimmune regulator

NM_000383

GTGLRCRSCSGDVTPAPVEGVLAPSPARLAPGPAKDDTASHEPALHRDDL