AKAP10 Antilichaam - middengebied HRP (ARP36326_P050-HRP)

A kinase (PRKA) anchor protein 10

PRKA10, AKAP-10, D-AKAP2, D-AKAP-2

11216

O43572

NP_009133

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human AKAP10

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA; therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.

COG3; DCTN4; MYH9; PRKAR1A; HAX1; SLC9A3R1; PDZK1; PRKAR2B; PRKAR2A

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

AKAP10 is supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Cow: 93%; Dog: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 90%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

71kDa

Wet Ice

662

AKAP10

AKAP10

Rabbit

A-kinase anchor protein 10, mitochondrial

NM_007202

ESLYQRTYAGKMTFGRVSDLGQFIRESEPEPDVRKSKGSMFSQAMKKWVQ