AKAP7 Antilichaam - middengebied: HRP (ARP36332_T100-HRP)

A kinase (PRKA) anchor protein 7

AKAP15, AKAP18

9465

Q9P0M2

NP_057461

Human, Mouse, Rat, Cow, Dog, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human AKAP7

AKAP7 is a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined.This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined.

CEP76; ROPN1; SPA17; PRKAR2B; PRKACB; PRKACA; MEPCE; USP4; PRKAR1A; PRKAR2A

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

AKAP7 is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 83%; Dog: 91%; Horse: 92%; Human: 100%; Mouse: 79%; Rabbit: 93%; Rat: 86%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

37kDa

Gold, M.G., (2008) J. Mol. Biol. 375 (5), 1329-1343

Wet Ice

326

AKAP7

AKAP7

Rabbit

A-kinase anchor protein 7 isoform gamma

NM_016377

MKLSKSPWLRKNGVKKIDPDLYEKFISHRFGEEILYRIDLCSMLKKKQSN