AKAP8 Antilichaam - middengebied: HRP (ARP32755 P050-HRP)

A kinase (PRKA) anchor protein 8

AKAP-8, AKAP95, AKAP 95, AKAP-95

10270

O43823

NP_005849

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast

The immunogen is a synthetic peptide directed towards the middle region of human AKAP8

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP8 is a member of the AKAP family. It is located in the nucleus during interphase and is distinctly redistributed during mitosis. This protein has a cell cycle-dependent interaction with the RII subunit of PKA.The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is located in the nucleus during interphase and is distinctly redistributed during mitosis. This protein has a cell cycle-dependent interaction with the RII subunit of PKA. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

SUMO2; UBC; RPA3; RPA2; RPA1; BMI1; RNF2; EZH2; HIPK4; HDAC11; CSNK2A1; MYC; ESR1; BARD1; LRRK2; CAND1; COPS5; CUL3; HNRNPA1; ELAVL1; Mis12; Aurkb; TADA2A; CASP3; DDX5; PRKAR2A; CCND1; RELA; CCND3; CCND2; MCM2; AMY1C; AMY1A

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

AKAP8 is strongly supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 85%; Rat: 92%; Yeast: 83%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

76kDa

Olsen, J.V., (2006) Cell 127 (3), 635-648

Wet Ice

692

AKAP8

AKAP8

Rabbit

A-kinase anchor protein 8

NM_005858

CKFRSFDDEEIQKHLQSKFHKETLRFISTKLPDKTVEFLQEYIVNRNKKI