
Akt1 (Myr) Adenovirus (Ad-CMV-Akt1 (Myr))
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
HA-Akt1 is constructed by fusing the HA tag in frame to the N termini of the coding sequence of wild type Akt1. To construct Myr-HA-Akt1, the c-Src myristoylation sequence was fused in frame to the N terminus of the HA-Akt (wild-type) coding sequence. Myr-HA-Akt1 is a constitutively active mutant of Akt1, and it is also referred as Akt (ca) .Akt1/PKB is activated in response to many extracellular signals and play key roles in regulating diverse cellular processes, including cell proliferation, differentiation, apoptosis, angiogenesis and glycogen synthesis etc. Akt1 is activated by the phosphorylation of the T loop of their kinase domain by PDK1 and by phosphorylation of a residue located C-terminal to the kinase domain in the hydrophobic motif. The Akt family of kinases includes Akt1, Akt2 and Akt3.
Akt1 (Myr) Adenovirus
41106621
3822190000
Pre-Made
Dry Ice
-80C
12 Months
Ad-CMV-Akt1 (Myr)
Human Adenovirus Type5 (dE1/E3)
CMV (ubiquitous)
HA
DMEM, 2% BSA, 2.5% Glycerol
1x10^10 PFU/ml
Beschrijving
HA-Akt1 is constructed by fusing the HA tag in frame to the N termini of the coding sequence of wild type Akt1. To construct Myr-HA-Akt1, the c-Src myristoylati
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