AKT2 Antilichaam

Murine thymoma viral (v-akt) homolog-2; rac protein kinase β . AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore, AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.

208

P31751

NP_001617.1

Human

108-124

Unconjugated

Primary Antibodies

Apoptosis, Neuroscience, Signal Transduction

Antigen affinity-purified

1 mg/mL

Phosphate-Buffered Saline. No preservatives added.

None

Blue Ice

AKT2 antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

55.8 kDa (calculated)

AKT2 antibody can be used for the detection of AKT2 by Western blot, ELISA, may also work for IHC and ICC.

AKT2

V-akt murine thymoma viral oncogene homolog 2

Homo sapiens

Cheng, J. Q., Ruggeri, B., Klein, W. M., Sonoda, G., Altomare, D. A., Watson, D. K., Testa, J. R. Amplification of AKT2 in human pancreatic cancer cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA. Proc. Nat. Acad. Sci. 93: 3636-3641, 1996.

Protein kinase Akt-2, PKB beta, PKBB, PRKBB, HIHGHH, PKBBETA, RAC-BETA

ELISA

4502023

Liquid