ALAS1 Mouse Monoclonal Antibody [Kloon ID: LBI1C5]

This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]

Carrier-free (BSA/glycerol-free) ALAS1 mouse monoclonal antibody, clone LBI1C5

ALAS; ALAS-H; ALAS3; ALASH; MIG4

Homo sapiens 5'-aminolevulinate synthase 1 (ALAS1), transcript variant 1, mRNA; nuclear gene for mitochondrial product.

211

P13196

Unconjugated

Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin and chlorophyll metabolism

Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin and chlorophyll metabolism

WB 1:2000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

ALAS1

https://www.ncbi.nlm.nih.gov/gene/?term=211

https://www.uniprot.org/uniprot/P13196