Albomycine δ2

Albomycin δ2 is a siderophore-antibiotic conjugate targeting bacterial ribosomes (MIC: 0.0625 μg/mL against S. pneumoniae, 0.125 μg/mL against MRSA) . Albomycin δ2 is promising for research of Streptococcus pneumoniae and Staphylococcus aureus infections[1][2].

34755-52-7

12352005

Antibiotic; Bacterial

Anti-infection

Infection

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C37H57FeN12O18S

1045.83

[1]Lin Z, et al. Total synthesis and antimicrobial evaluation of natural albomycins against clinical pathogens. Nat Commun. 2018 Sep 4;9 (1) :3445.|[2]Gadakh B, et al. Synthesis and structural insights into the binding mode of the albomycin δ1 core and its analogues in complex with their target aminoacyl-tRNA synthetase. Bioorg Med Chem. 2020 Sep 1;28 (17) :115645.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N16460/

Natural Products

No Development Reported