ALDH18A1 Antilichaam

This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.

5832

P54886

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ALDH18A1 (NP_002851.2) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

U-87MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 87kDa

IgG

WB: 1:500 - 1:2000

ALDH18A1

Mouse testis

Rat brain

Aldehyde dehydrogenase 18 family, member A1

Homo sapiens

ALDH18A1, pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase), PYCS, P5CS, MGC117316, GSAS, delta1-pyrroline-5-carboxlate synthetase, aldehyde dehydrogenase 18A1, aldehyde dehydrogenase 18 family, member A1

WB

Liquid