ALDH5A1 Antilichaam - middengebied: HRP (ARP59587 P050-HRP)

Aldehyde dehydrogenase 5 family, member A1

SSDH, SSADH

7915

P51649

NP_001071

Human, Rat, Cow, Guinea Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human ALDH5A1

This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD (+) -dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA) . In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.

MAGEA11; TOMM40; VDAC1; TIAL1; SSBP1; SOD2; EBNA-LP; ABAT

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 86%; Guinea Pig: 79%; Human: 100%; Rabbit: 79%; Rat: 86%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

57kDa

Wet Ice

535

ALDH5A1

ALDH5A1

Rabbit

Succinate-semialdehyde dehydrogenase, mitochondrial

NM_001080

AFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAM