ALDOA Antibody - N-terminal regio : HRP (ARP48130_T100-HRP)

Aldolase A, fructose-bisphosphate

ALDA, GSD12, HEL-S-87p

226

P04075

NP_000025

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human ALDOA

ALDOA is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia.This gene product, Aldolase A (fructose-bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode the same protein.

HUWE1; UBC; IFNA4; FUS; ALDOC; ALDOA; SUMO2; SUMO3; MDM2; ADRB2; SUZ12; TNPO3; CS; RAD52; VCPKMT; PIAS4; GALNT6; IQCB1; VCAM1; MLH1; ITGA4; HSP90AB1; HSP90AA1; FN1; ATF2; BCAT2; ALDOB; LIG4; PGK1; LGALS1; HSPD1; AKT1; MYOC; CDK2; CUL2; CUL3; CUL4B; ISG15

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 93%; Sheep: 82%; Zebrafish: 92%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

39kDa

Lu, J., (2008) Biochem. Biophys. Res. Commun. 369 (3), 948-952

Wet Ice

364

ALDOA

ALDOA

Rabbit

Fructose-bisphosphate aldolase A

NM_000034

MPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTE