Alectinib
Gecertificeerd

Alectinib

Catalog #: bs-83023C-01
Maat: 5 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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BTW niet inbegrepen
Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Background

Alectinib is a potent (IC50 = 1.9 nM) and highly selective ALK inhibitor.1 It blocked phosphorylation of both native ALK and the L1196M, C1156Y, and F1174L mutants. Alectinib has also been shown to inhibit RET kinase (IC50 = 4.8 nM), the RET gatekeeper mutations V804L and V804M, and inhibited the growth of RET fusion positive cells.2 Alectinib is clinically useful in the treatment of ALK-positive Non-Small Cell Lung Cancer. It effectively suppressed cell proliferation and induced apoptosis in a mouse neuroblastoma xenograft.3

Conjugation

Unconjugated

Buffer

White solid

Storage Conditions

-20°C

Beschrijving

Alectinib Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamAlectinib
Categorie
Beschikbare grootte5 mg
Catalogusnummerbs-83023C-01