Alfa-synucleïne-antilichaam / SNCA

Mutations or abnormal accumulation of Alpha-Synuclein are strongly linked to synucleinopathies, including Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. Its aggregation into insoluble fibrils is a key pathological hallmark of these conditions. Studying Alpha-Synuclein expression and distribution provides valuable insights into neuronal function, protein misfolding, and neurodegenerative disease mechanisms. Using a high-quality Alpha-Synuclein antibody enables sensitive detection in assays such as western blot, immunohistochemistry, and ELISA. An Alpha-Synuclein antibody from NSJ Bioreagents offers reliable performance for researchers investigating protein aggregation, neurodegenerative disease progression, and potential therapeutic interventions. Selecting the appropriate Alpha-Synuclein antibody is essential for generating reproducible and accurate results in both basic and applied neuroscience research.

Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200, Immunofluorescence: 1:50-1:200

P37840

Human, Mouse, Rat

A peptide sequence specific to Alpha-Synuclein was used as the immunogen for the Alpha-Synuclein antibody.

AGA-19

WB, IF, IHC-P

Affinity chromatography

Purified

This Alpha-Synuclein antibody is available for research use only.

After reconstitution, the Alpha-Synuclein antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Optimal dilution of the Alpha-Synuclein antibody should be determined by the researcher.

Nuclear, cytoplasmic, cell membrane

IHC staining of FFPE human colon cancer tissue with Alpha-Synuclein antibody, HRP-secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.