ALG10 Antilichaam

ALG10 encodes a membrane-associated protein that adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. That is, it transfers the terminal glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc (2) -PP-Dol. The rat protein homolog was shown to specifically modulate the gating function of the rat neuronal ether-a-go-go (EAG) potassium ion channel.

84920

Q5BKT4

Q5BKT4

Human

This ALG10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-43 amino acids from the N-terminal region of human ALG10.

Unconjugated

Primary Antibodies

Other

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

56 kDa

Rabbit Ig

ALG10

Dol-P-Glc:Glc (2) Man (9) GlcNAc (2) -PP-Dol alpha-1,2-glucosyltransferase

Homo sapiens

Chapuis, J., et al. Mol. Psychiatry 14 (11) :1004-1016 (2009)

Seshadri, S., et al. BMC Med. Genet.SUPPL 1, S15 (2007)

Kupershmidt, S., et al. FASEB J. 17 (15) :2263-2265 (2003)

Dol-P-Glc:Glc (2) Man (9) GlcNAc (2) -PP-Dol alpha-1,2-glucosyltransferase, Alpha-1,2-glucosyltransferase ALG10-A, Alpha-2-glucosyltransferase ALG10-A, Asparagine-linked glycosylation protein 10 homolog A, ALG10, ALG10A

WB, IHC-P

74736030

Liquid