ALG.APV-527
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
ALG.APV-527 (APV-527) is a bispecific 4-1BB (CD137) and 5T4 antibody. ALG.APV-527 is designed to activate 4-1BB on T and natural killer (NK) cells only when simultaneously bound to 5T4-expressing tumor cells. ALG.APV-527 has a potent antitumor activity[1].
APV-527; ATOR-1016
12352203
Transmembrane Glycoprotein
Immunology/Inflammation
Cancer-programmed cell death
Cancer
[ALG.APV-527]
[1]Nelson MH, et al. The Bispecific Tumor Antigen-Conditional 4-1BB x 5T4 Agonist, ALG.APV-527, Mediates Strong T-Cell Activation and Potent Antitumor Activity in Preclinical Studies. Mol Cancer Ther. 2023 Jan 3;22 (1) :89-101.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991095/
Inhibitory Antibodies
Phase 2
Beschrijving
ALG.APV-527 (APV-527) is a bispecific 4-1BB (CD137) and 5T4 antibody. ALG.APV-527 is designed to activate 4-1BB on T and natural killer (NK) cells only when sim
Specificaties
Recent bekeken producten
SCD polyclonal antibody
GTR18043932-01
50 μL
(KO Validated) SUMO1 Polyclonal Antibody
E-AB-92410-01
60 µL
Salicylate hydroxylase, Microorganism
HY-E70520-01
1 KU
Purified Diphtheria Toxoid protein (cGMP/USP, vaccine grade, ~1500-2500 Lf/ml; Low endotoxin)
DTOX16-N-500
500 µg
BioCoupler® Glass Set (16 oz) x12
BCS1612
12 Each
BioCoupler® x 48
BC48
48 Each
BioTilt™ 25 (BT25)
BT25
25 Bundles
Purified Diphtheria Toxoid protein (antigen grade)
DTOX15-N-500
100 µg
Recent gezochte producten
SMRCD Polyclonal Antibody
JOT-AP14328-01
20 µL
MYCD Polyclonal Antibody
JOT-AP11603-01
20 µL
Anti-DCD Polyclonal Antibody
HX130014-01
50 µg
Anti-MYOCD Polyclonal Antibody
HV334024-01
50 µg
Anti-Human FTCD Polyclonal Antibody
HF652014-01
50 µg
Anti-Human PIK3CD Polyclonal Antibody
HT068014-01
50 µg
Anti-Human PRCD Polyclonal Antibody
HD164014-01
50 µg
SCD polyclonal antibody
GTR18043932-01
50 μL