Alloc-Val-Ala-OH
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
330970-70-2
Alloc-Val-Ala-OH (((Allyloxy) carbonyl) -L-valyl-L-alanine) serves as a building block in the synthesis of Tesirine, which is a clinical antibody-drug conjugate (ADC) featuring a pyrrolobenzodiazepine (PBD) dimer payload. The Val-Ala sequence is cleaved specifically by cathepsin B. The Alloc group is stable towards piperidine and TFA, yet can be easily removed under mild conditions via palladium-catalyzed allyl transfer.
[C@H](C(N[C@H](C(O)=O)C)=O)(NC(OCC=C)=O)C(C)C
C12H20N2O5
272.298
Ice Packs
-20°C
Beschrijving
Alloc-Val-Ala-OH Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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