Alloc-Val-Ala-pAB
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Alloc-Val-Ala-PAB is a peptide cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) . The Val-Ala will specifically be cleaved by Cathepsin B. The Alloc group is stable to treatment with piperidine and TFA, but can be easily removed under mild conditions by palladium catalyzed allyl transfer.
1343407-91-9
12352005
H302, H315, H319, H335
ADC Linker
Antibody-drug Conjugate/ADC Related
Cancer-programmed cell death
Cancer
99.61
OCC1=CC=C(NC([C@@H](NC([C@@H](NC(OCC=C)=O)C(C)C)=O)C)=O)C=C1
C19H27N3O5
377.43
H302, H315, H319, H335
Room Temperature
-20°C, 3 years; 4°C, 2 years (Powder)
http://file.medchemexpress.com/batch_PDF/HY-W071967/
Reference compound1
No Development Reported
Beschrijving
Alloc-Val-Ala-PAB is a peptide cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) . The Val-Ala will specifically be cleaved by Cathepsin
Specificaties
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