Aloëson

Aloesone is a phenolic compound. Aloesone can inhibit the production of ROS, the release of NO, M1 polarization, and apoptosis in RAW264.7 cells stimulated by LPS. Aloesone has anti-inflammatory and antioxidant activities[1][2].

40738-40-7

12352005

H302, H315, H319, H335

Apoptosis; Reactive Oxygen Species (ROS)

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

COVID-19-immunoregulation

Inflammation/Immunology

99.49

DMSO : 100 mg/mL (ultrasonic)

O=C1C=C(CC(C)=O)OC2=CC(O)=CC(C)=C12

C13H12O4

232.23

H302, H315, H319, H335

[1]Reza Nazifi SM, et al. Antioxidant properties of Aloe vera components: a DFT theoretical evaluation. Free Radic Res. 2019 Aug;53 (8) :922-931.|[2]Wang Y, et al. Multiple Beneficial Effects of Aloesone from Aloe vera on LPS-Induced RAW264.7 Cells, Including the Inhibition of Oxidative Stress, Inflammation, M1 Polarization, and Apoptosis. Molecules. 2023 Feb 8;28 (4) :1617.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-N8559/Aloesone-SDS-MedChemExpress.pdf

Natural Products

No Development Reported