Alsterpaullon
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
237430-03-4
Alp, 9-Nitropaullone, NSC 705701
C07144-5mg
CDK
Cell Cycle
C1C2=C (C3=CC=CC=C3NC1=O) NC4=C2C=C (C=C4) [N+] (=O) [O-]
C16H11N3O3
Alsterpaullone (Alp, 9-Nitropaullone, NSC 705701) is a potent inhibitor of CDK with IC50 of 35 nM, 15 nM, 200 nM and 40 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E and CDK5/p35, respectively. Alsterpaullone also acts as a potent inhibitor of glycogen synthase kinase-3 (GSK-3) with IC50 of both 4 nM for GSK-3α and GSK-3β. Alsterpaullone induces apoptosis by activation of caspase-9. Alsterpaullone has antitumor activity and possesses potential for the treatment of neurodegenerative and proliferative disorders.
3 years -20°C powder
Beschrijving
Alsterpaullon Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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