AMACR Antilichaam - middengebied: Biotine (ARP60807 P050-Biotine)

Alpha-methylacyl-CoA racemase

RM, RACE, CBAS4, P504S, AMACRD

23600

F8W9N1

NP_001161067

Human, Rat, Cow, Dog, Horse, Pig, Rabbit

This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R) - and (S) -stereoisomers. The conversion to the (S) -stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

UBC; PEX5

Biotin

Polyclonal Antibody

WB

Affinity Purified

AMACR is strongly supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Cow: 86%; Dog: 85%; Horse: 85%; Human: 100%; Pig: 85%; Rabbit: 79%; Rat: 91%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

43kDa

Wet Ice

394

AMACR

AMACR

Rabbit

Alpha-methylacyl-CoA racemase Ensembl ENSP00000371517

NM_001167595

SGENPYAPLNLLADFAGGGLMCALGIIMALFDRTRTGKGQVIDANMVEGT