AMACR Mouse Monoclonal Antibody [Kloon ID: LBI2A11]

This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R) - and (S) -stereoisomers. The conversion to the (S) -stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]

Carrier-free (BSA/glycerol-free) AMACR mouse monoclonal antibody, clone LBI2A11

AMACRD; CBAS4; RACE; RM

Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 1, mRNA.

23600

Q9UHK6

Unconjugated

Metabolic pathways, Primary bile acid biosynthesis

Metabolic pathways, Primary bile acid biosynthesis

WB 1:2000, IHC 1:150

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

AMACR

https://www.ncbi.nlm.nih.gov/gene/?term=23600

https://www.uniprot.org/uniprot/Q9UHK6