Amarogentin
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
21018-84-8
AG
C07674-5mg
Taste Receptor
GPCR & G Protein
OCC1OC (OC2OC=C3C (CCOC3=O) C2C=C) C (OC (=O) C4=C (O) C=C (O) C=C4C5=CC=CC (=C5) O) C (O) C1O
C29H30O13
Amarogentin (AG), a secoiridoid glycoside mainly extracted from Swertia and Gentiana roots, exhibits anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin is an agonist for the bitter taste receptor TAS2R1 and inhibits in LAD-2 cells substance P-induced production of newly synthesized TNF-α. Amarogentin induces apoptosis in human gastric cancer cells (SNU-16) through G2/M cell cycle arrest and PI3K/Akt signalling pathway. Amarogentin (AG) interacts with the α2 subunit of AMP-activated protein kinase (AMPK) and activates the trimeric kinase with EC50 of 277 pM.
3 years -20°C powder
Beschrijving
Amarogentin Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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