AMFR Antilichaam - C-terminaal gebied: Biotine (ARP42995 T100-Biotine)

Autocrine motility factor receptor, E3 ubiquitin protein ligase

GP78, RNF45

267

Q9UKV5

AAH56869

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human AMFR

Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. AMFR is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000) .[supplied by OMIM].

VCP; UBE2G1; HSPA5; ERLIN2; INSIG1; HMGCR; DHFR; AMFR; UBE2D1; UBC; GPI; TRIM25; DGAT2; UBE2K; Ube2g2; NPLOC4; HERPUD1; BAG6; MAVS; YOD1; ADRA1D; DERL2; ADRB2; FAF2; SEC61B; RPN1; STT3A; STT3B; AUP1; MDC1; SNED1; DDOST; GET4; UBXN4; UBL4A; CD82; SARAF; IT

Biotin

Polyclonal Antibody

WB

AMFR is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

73kDa

Lehner, B. (2004) Genome Res. 14 (7), 1315-1323

Wet Ice

643

AMFR

AMFR

Rabbit

AMFR protein EMBL AAH56869.1

NM_013446

FGEVEVEPSEVEDFEARGSRFSKSADERQRMLVQRKDELLQQARKRFLNK