AMG-529
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
AMG-529 is a humanized anti-ASGR1 monoclonal antibody that binds to ASGR1 and blocks ligand binding, resulting in dose-induced increases in ALP, a biomarker of ASGR1 inhibition[1].
12352203
Phosphatase
Metabolic Enzyme/Protease
Metabolism-sugar/lipid metabolism
Metabolic Disease
97.41
[AMG-529]
[1]Janiszewski, M., et al. A RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND, ASCENDING SINGLE-DOSE, PHASE 1 STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF AMG 529, A NOVEL ANTI-ASGR1 MONOCLONAL ANTIBODY, IN HEALTHY SUBJECTS. Journal of the American College of Cardiology, 73 (9), 1755.
Dry Ice
-80°C
http://file.medchemexpress.com/batch_PDF/HY-P991222/AMG-529-SDS-MedChemExpress.pdf
Inhibitory Antibodies
No Development Reported
Beschrijving
AMG-529 is a humanized anti-ASGR1 monoclonal antibody that binds to ASGR1 and blocks ligand binding, resulting in dose-induced increases in ALP, a biomarker of
Specificaties
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