AMG-780
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
AMG-780 is a fully human IgG2 antibody that targets angiopoietin 1 (Ang1) (IC50 = 4.5 nM) and angiopoietin 2 (Ang2) (IC50 = 0.06 nM) . AMG-780 inhibits tumor growth in the Colo205 xenograft mouse model by inhibiting both Ang1 and Ang2. AMG-780 is indicated for the research of cancers such as colon cancer[1][2].
12352100
Tie
Protein Tyrosine Kinase/RTK
Cancer
[1]James V. Bready, et al. Abstract 1022: Development and preclinical testing of AMG 780, a fully human antibody targeting angiopoietin 1 (Ang1) and angiopoietin 2 (Ang2) . Cancer Res 1 October 2014; 74 (19_Supplement) : 1022. |[2]James V. Bready, et al. Abstract 1022: Development and preclinical testing of AMG 780, a fully human antibody targeting angiopoietin 1 (Ang1) and angiopoietin 2 (Ang2) . Cancer Res 1 October 2014; 74 (19_Supplement) : 1022.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991663/
Inhibitory Antibodies
No Development Reported
Beschrijving
AMG-780 is a fully human IgG2 antibody that targets angiopoietin 1 (Ang1) (IC50 = 4.5 nM) and angiopoietin 2 (Ang2) (IC50 = 0.06 nM) . AMG-780 inhibits tumor gr
Specificaties
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