AMG-966
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
AMG-966 is a human bispecific antibody (bsAb) targeting TNFSF15/TL1A & TNFα. AMG 966 restores the ability of the aglycosylated Fc domain to bind to FcγRIa and FcγRIIa, leading to the formation of antidrug antibodies (ADA). AMG-966 can be used in Crohn's disease and Ulcerative colitis research. Recommended isotype control: Human IgG1 kappa, Isotype Control.
12352203
TNF Receptor
Apoptosis
COVID-19-immunoregulation
Inflammation/Immunology
96.19
[AMG-966]
(145.25 kDa)
[1]Kroenke MA, et al. Immune Complex Formation Is Associated With Loss of Tolerance and an Antibody Response to Both Drug and Target. Front Immunol. 2021 Dec 14;12:782788.
Dry Ice
-80°C
http://file.medchemexpress.com/batch_PDF/HY-P991440/AMG-966-SDS-MedChemExpress.pdf
Inhibitory Antibodies
No Development Reported
Beschrijving
AMG-966 is a human bispecific antibody (bsAb) targeting TNFSF15/TL1A & TNFα. AMG 966 restores the ability of the aglycosylated Fc domain to bind to FcγRIa and F
Specificaties
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BioCoupler® Glass Set (16 oz) x12
BCS1612
12 Each
BioCoupler® x 48
BC48
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BioTilt™ 25 (BT25)
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25 Bundles
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