AMHR2 Polyklonale Antilichaam

MISR II is a 573 amino acid protein encoded by the human gene AMHR2. MISR II belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily and contains one protein kinase domain. Upon ligand binding, MISR II forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. These type II receptors rylate and activate type I receptors which autophosphorylate, then bind and activate Smad transcriptional regulators. MISR II also acts as a receptor for anti-Muellerian hormone. Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS-2) . PMDS-2 is a form of male pseudo-hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.

AMH type II receptor; AMHR2; AMHR2_HUMAN; Anti-Muellerian hormone type II receptor; Anti-Muellerian hormone type-2 receptor; MGC141312; MIS type II receptor; MISRII; MRII; Muellerian hormone type 2 receptor; Muellerian hormone type II receptor; Mullerian hormone receptor type II.

269

Cell membrane

Human, Mouse, Rat

21-120/573

AMHR2

Unconjugated

KLH conjugated synthetic peptide derived from human MISRII/AMHR2

WB, ELISA, FCM, IHC-P

Purified by Protein A.

1µg/µl

WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400)

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

269

Dog, Pig, Horse