AMIGO1 Antilichaam

The amphoterin-induced gene and ORF (AMIGO1) protein is a brain-enriched, glycosylated transmembrane immunoglobulin (Ig) superfamily protein with six extracellular leucine-rich repeats (LRRs) and one Ig-like domain. It and the related proteins AMIGO2 and AMIGO3 are thought to be cell adhesion molecules expressed on fiber tracts of neuronal tissues and participate in their formation (1) . AMIGO1 has also been suggested to play important roles in dendritic outgrowth during development and could modulate the survival of developing and adult neurons (2) .

57463

Q86WK6

NP_065754

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Neuroscience

AMIGO1 antibody is affinity chromatography purified via peptide column.

Cat. No. 1201 - HeLa Cell Lysate

1 mg/mL

AMIGO1 antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

AMIGO1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

AMIGO1 antibody is human, mouse, and rat reactive. AMIGO1 antibody is predicted to not cross-react with AMIGO2 or AMIGO3.

AMIGO1

Cat. No. 10-301 - Human Brain Tissue Slide

Adhesion molecule with Ig-like domain 1

Homo sapiens

Kuja-Panula J, Kiiltomaki M, Yamashiro T, et al. AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats. J. Cell Biol. 2003; 160:963-73.

Chen Y, Hor HH, and Tang BL. AMIGO is expressed in multiple brain cell types and may regulate dendritic growth and neuronal survival. J. Cell Physiol. 2012; 227:2217-29.

AMIGO1 Antibody: ALI2, AMIGO, AMIGO-1, ALI2, KIAA1163, Amphoterin-induced protein 1

ELISA, WB, IHC-P, IF

153791466

Liquid