Amiloride (Standaard)

Amiloride (Standard) is the analytical standard of Amiloride. This product is intended for research and analytical applications. Amiloride (MK-870) is an inhibitor of both epithelial sodium channel (ENaC[1]) and urokinase-type plasminogen activator receptor (uTPA[2]) . Amiloride is a blocker of polycystin-2 (PC2; TRPP2[3]) channel.

2609-46-3

12352100

Apoptosis; Reference Standards; Sodium Channel; TRP Channel

Apoptosis; Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Metabolic Disease; Cardiovascular Disease

O=C(C1=NC(Cl)=C(N)N=C1N)NC(N)=N

C6H8ClN7O

229.63

[1]Ji, H.L., et al. delta ENaC: a novel divergent amiloride-inhibitable sodium channel. Am J Physiol Lung Cell Mol Physiol, 2012. 303 (12) : p. L1013-26.|[2]Teiwes J, et al. Epithelial sodium channel inhibition in cardiovascular disease. A potential role for amiloride. Am J Hypertens. 2007 Jan;20 (1) :109-17.|[3]Giamarchi A, et al. A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. EMBO J. 2010 Apr 7;29 (7) :1176-91.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-B0285R/

Reference Standards