Aminoguanidine (hydrochloride) (standaard)

Aminoguanidine (hydrochloride) (Standard) is the analytical standard of Aminoguanidine (hydrochloride). This product is intended for research and analytical applications. Aminoguanidine hydrochloride (Pimagedine hydrochloride) is an inhibitor of diamine oxidase and nitric oxide synthase. Aminoguanidine hydrochloride has a dose-dependent inhibitory effect on apoptosis induced by Doxorubicin. Aminoguanidine hydrochloride has antioxidant properties. Aminoguanidine hydrochloride can be used in diabetic nephropathy research[1][2][3][4].

1937-19-5

12352100

H317-H401-H411

Apoptosis; NO Synthase; Reference Standards

Apoptosis; Immunology/Inflammation; Others

Endocrinology

NNC(N)=N.[H]Cl

CH7ClN4

110.55

P261-P272-P273-P280-P302+P352-P363-P391-P501

[1]Sabuncuoglu S. Antiapoptotic effect of aminoguanidine on doxorubicin-induced apoptosis. Mol Cell Biochem. 2014 Sep;394 (1-2) :129-35.|[2]Chowdhury P. Aminoguanidine (AG) Induces Induced both Pro- and Antioxidant Effect in AR42J Cells, a Rat Pancreatic Tumor Cell Line. Ann Clin Lab Sci. 2017 Sep;47 (5) :572-580. PMID: 29066484.|[3]Al-Shabanah OA, et al. Protective effect of aminoguanidine, a nitric oxide synthase inhibitor, against carbon tetrachloride induced hepatotoxicity in mice. Life Sci. 2000;66 (3) :265-70.|[4]Abraham P, et al. Protective effect of aminoguanidine against cyclophosphamide-induced oxidative stress and renal damage in rats. Redox Rep. 2011;16 (1) :8-14.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-B1041R/

Reference Standards