AMPK alpha 1 Antilichaam

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK) . AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

5562

Q13131

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human AMPK alpha 1 (NP_006242.5) .

Unconjugated

Primary Antibodies

Apoptosis, Autophagy, Cancer, Cell Cycle, Neuroscience, Signal Transduction

Affinity purification

Mouse kidney

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 65kDa

IgG

PRKAA1

Mouse spleen

Protein kinase, AMP-activated, alpha 1 catalytic subunit

Homo sapiens

PRKAA1, AMPK, AMPKa1, MGC33776, MGC57364

WB, IF

Liquid