Amylineagonist 1
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Amylin agonist 1 (Example 239a) is a receptor 3 for pancreatic amyloid peptide (bAMY3R) agonist, and its EC50 for stimulating cAMP production in cells is 6.17 nM. Amylin agonist 1 is also a receptor for calcitonin (bCTR) agonist, with its EC50 being 8.58 nM. Amylin agonist 1 can be used for research on type 2 diabetes and obesity[1].
12352005
Amylin Receptor; CGRP Receptor
GPCR/G Protein; Neuronal Signaling
Metabolic Disease
CC(CC1=C(C(C2=CC=C3C(OCC(N3CC4=NC=C(C=N4)Cl)=O)=C2)=C5C=NN(C5=N1)C6CCN(CC6C)C7COC7)C(N)=O)C
C33H37ClN8O4
645.15
[1]Renato A, et al. 4-phenyl-1h-pyrazolo[3,4-b]pyridine-5-carboxamide derivatives as amylin and/or calcitonin receptor agonists for the treatment of type 2 diabetes, obesity or overweight. WO2025240893A1.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-179728/
Reference compound1
No Development Reported
Beschrijving
Amylin agonist 1 (Example 239a) is a receptor 3 for pancreatic amyloid peptide (bAMY3R) agonist, and its EC50 for stimulating cAMP production in cells is 6.17 n
Specificaties
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