ANEG Antilichaam

The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha) . The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions.

374

P15514

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 20-252 of human AREG (NP_001648.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Signal Transduction

Affinity purification

Mouse testis

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 44kDa

IgG

AREG

Rat testis

Amphiregulin

Homo sapiens

Amphiregulin, AR, Colorectum cell-derived growth factor, CRDGF, AREG, SDGF

WB, IHC, IF

Liquid