Angiopoëtine zoals 4 (ANGPTL4) (NM 139314) Humaan Recombinant Proteïne

This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013]

Purified recombinant protein of Human angiopoietin-like 4 (ANGPTL4), transcript variant 1, Gln53-Ser301, with N-terminal His tag, expressed in E. coli, 50ug

ARP4; FIAF; HARP; HFARP; NL2; PGAR; pp1158; TGQTL; UNQ171

51129

Q9BY76

NM_139314

19p13.2

E. coli

N-His

PPAR signaling pathway

PPAR signaling pathway

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Druggable Genome, Secreted Protein

28.3 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

ANGPTL4

Human

NP_647475

https://www.ncbi.nlm.nih.gov/gene/51129

https://www.uniprot.org/uniprot/Q9BY76

https://www.ncbi.nlm.nih.gov/nuccore/NM_139314

https://www.ncbi.nlm.nih.gov/nuccore/NP_647475